HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Acetylphenylboronic acid → HCID 86594580, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Acetylphenylboronic acid | HCID 3702122 | — |
| Reactant | HCID 86594560 | HCID 86594560 | — |
| Product | HCID 86594580 | HCID 86594580 | — |
Reaction Steps
N2-(4-bromoisothiazol-3-yl)-N1-(cyanomethyl)leucinamide (100 mg, 0.30 mmol, prepared as described in Example 13) was submitted to a Suzuki coupling with 4-acetylphenylboronic acid (99 mg, 0.60 mmoles) as described in Example 1 to afford N2-[4-(4-acetylphenyl)isothiazol-3-yl]-N1-(cyanomethyl)leucinamide which was purified by flash chromatography (30% to 55% EtOAc/hexanes).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07012075B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-73926c9f88a440ea84e8d23a0a2656c2 |
| Source note | uspto-grants-2006_03 |