Ethanethiol → HCID 22228620, compound

Participants

Reaction Steps

34 mg (0.09 mmol) of ethyl 2-[6-(3-isopropyl-4-methoxyphenoxy)-5,7-dimethyl-1-benzofuran-3-yl]acetate in 3 ml of dichloromethane are added, at 0° C., to 34 mg (0.26 mmol) of aluminum trichloride and 83 mg (1.3 mmol) of ethanethiol. The mixture is stirred at room temperature for 6 hours, concentrated in vacuo and purified chromatographically (toluene/ethyl acetate). 24 mg (73%) of ethyl 2-[6-(4-hydroxy-3-isopropylphenoxy)-5,7-dimethyl-1-benzofuran-3-yl]acetate are obtained.

Provenance & Evidence