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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1744351Generated: November 1, 2026

4-(2-Piperidin-1-yl-ethoxy)-phenylamine → HCID 178418766, compound

https://huagongshe.com/reaction/1744351

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Piperidin-1-yl-ethoxy)-phenylamineHCID 3016025—
Reactant3-(hydroxymethylidene)-1H-indol-2-oneHCID 178418741—
ProductHCID 178418766HCID 17841876680%

Reaction Steps

In a manner similar to that described in Example 231, 4-(2-piperidin-1-yl-ethoxy)-phenylamine (820 mg, 1.2 equiv.) and 3-hydroxymethylene-1,3-dihydro-indol-2-one (500 mg, 3.11 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (899 mg, 80%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07015220B2
Source datasetuspto-grants-2006_03
ORD IDord-04afa9aaf19c4a7e84c4436a5e08c96f
Source noteuspto-grants-2006_03