3-Methoxyphenol → HCID 9884225, compound

HRID 1744439Notes

Reaction equation

[CH3:1][O:2][C:3]1C=C(O)[CH:6]=[CH:7][CH:8]=1.[CH2:10]([O:12][C:13](=[O:28])[C:14]([C:26]#[N:27])=[CH:15][C:16]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[C:18]([O:24][CH3:25])[CH:17]=1)[CH3:11]>>[C:26]([C:14]1[C:13](=[O:28])[O:12][C:10]2[C:6]([C:15]=1[C:16]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[C:18]([O:24][CH3:25])[CH:17]=1)=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:11]=2)#[N:27]

Participants

Reactant 2

HCID 90073-Methoxyphenol

HCID 2732672HCID 2732672, compound

Product 1

HCID 9884225HCID 9884225, compoundYield 4.2%

Procedure

The title compound was prepared from 3-methoxyphenol and 2-cyano-3-(3,5-dimethoxy-phenyl)-acrylic acid ethyl ester by a procedure similar to that described for Example 1 in 4.2% yield. 1H NMR (CDCl3): 7.36 (d, J=9.0, 1H), 6.89-6.83 (m, 2H), 6.65-6.63 (m, 1H), 6.55-6.54 (m, 2H), 3.93 (s, 3H), 3.85 (s, 6H).

Sources & evidence

ORD record: ord-55b80db7c0ae4aa8a03d061ae330b8e5
Source dataset: uspto-grants-2006_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07015328B2

Reaction notes

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