HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenelzine → 1H-Pyrazole-4-carboxylic acid, 3-methyl-1-(2-phenylethyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenelzine | HCID 3675 | — |
| Reactant | Butanoic acid, 2-(ethoxymethylene)-3-oxo-, ethyl ester | HCID 97734 | — |
| Product | 1H-Pyrazole-4-carboxylic acid, 3-methyl-1-(2-phenylethyl)- | HCID 22227926 | 37.1% |
Reaction Steps
By the reaction and treatment in the same manner as in Starting Material Synthesis Example 1 using phenelzine (15 g) and ethyl 2-ethoxymethyleneacetoacetate (12 g), the residue was recrystallized from a mixed solvent of ethyl acetate-diisopropyl ether to give 3-methyl-1-phenethylpyrazole-4-carboxylic acid (5.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07015218B1 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-1e65d4d6066749419e1be1d53a75070e |
| Source note | uspto-grants-2006_03 |