4-Morpholinopiperidine → 3-Bromo-4-(4-morpholinopiperidin-1-yl)aniline

HRID 1744543Notes

Reaction equation

HRID 1744543 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([N+:9]([O-])=O)[CH:5]=[CH:6][C:7]=1Cl.[O:12]1[CH2:17][CH2:16][N:15]([CH:18]2[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]2)[CH2:14][CH2:13]1>>[Br:1][C:2]1[CH:3]=[C:4]([CH:5]=[CH:6][C:7]=1[N:21]1[CH2:22][CH2:23][CH:18]([N:15]2[CH2:16][CH2:17][O:12][CH2:13][CH2:14]2)[CH2:19][CH2:20]1)[NH2:9]

Participants

3

Reactant 2

HCID 7957244-MorpholinopiperidineHCID 27355492-Bromo-1-chloro-4-nitrobenzene

Product 1

HCID 222280173-Bromo-4-(4-morpholinopiperidin-1-yl)aniline

Procedure

By the reaction and treatment in the same manner as in Starting Material Synthesis Example 40 using 3-bromo-4-chloronitrobenzene and 4-morpholinopiperidine, the title compound was obtained, melting point: 215–217° C.

Workup

  1. customBy the reaction and treatment in the same manner as

Sources & evidence

ORD record
ord-f3cae7b44b9e4d74b3666f21a3767fb1
Source dataset
uspto-grants-2006_03
Patent number
US07015218B1

Reaction notes

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