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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1744619Erstellt: 25. Oktober 2026

1-(2-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid → 1-(2-Chlorophenyl)-N-[3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamide

https://huagongshe.com/reaction/1744619

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(2-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acidHCID 10633602—
Edukt5-Amino-2-(4-morpholinopiperidin-1-yl)benzonitrileHCID 21942389—
Produkt1-(2-Chlorophenyl)-N-[3-cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methylpyrazole-4-carboxamideHCID 2222810937,3%

Reaktionsschritte

By the reaction and treatment in the same manner as in Example 64 using 1-(2-chlorophenyl)-5-methylpyrazole-4-carboxylic acid (1.0 g) and 5-amino-2-(4-morpholinopiperidin-1-yl)benzonitrile (1.2 g), the title compound (0.79 g) was obtained, melting point: 218° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07015218B1
Quelldatensatzuspto-grants-2006_03
ORD IDord-9f67a80b44b942d88037b9ad56f61348
Quellennotizuspto-grants-2006_03