Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(4-methoxyphenyl)-5-methyl-1H-pyrazole-4-carboxylic acid → N-[3-Cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-1-(4-methoxyphenyl)-5-methylpyrazole-4-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(4-methoxyphenyl)-5-methyl-1H-pyrazole-4-carboxylic acid | HCID 2776133 | — |
| 반응물 | 5-Amino-2-(4-morpholinopiperidin-1-yl)benzonitrile | HCID 21942389 | — |
| 생성물 | N-[3-Cyano-4-(4-morpholinopiperidin-1-yl)phenyl]-1-(4-methoxyphenyl)-5-methylpyrazole-4-carboxamide | HCID 22227976 | 62% |
반응 단계
By the reaction and treatment in the same manner as in Example 64 using 1-(4-methoxyphenyl)-5-methylpyrazole-4-carboxylic acid (1.0 g) and 5-amino-2-(4-morpholinopiperidin-1-yl) benzonitrile (1.2 g), the title compound (1.3 g) was obtained, melting point: 238° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07015218B1 |
| 출처 데이터셋 | uspto-grants-2006_03 |
| ORD ID | ord-d66218531e6c4c57a9146ee681ad0aa0 |
| 출처 메모 | uspto-grants-2006_03 |