HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22228017, compound → N-[3-Bromo-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22228017 | HCID 22228017 | — |
| Reactant | 5-Methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxylic chloride | HCID 22228086 | — |
| Product | N-[3-Bromo-4-(4-morpholinopiperidin-1-yl)phenyl]-5-methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxamide | HCID 22227978 | 60.3% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 150 using 5-methyl-1-(4-trifluoromethylphenyl)pyrazole-4-carboxylic chloride (1.7 g) and 3-bromo-4-(4-morpholinopiperidin-1-yl)aniline (2.0 g), the title compound (2.1 g) was obtained, melting point: 220–230° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07015218B1 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-cf521865b35048598bd823e08e6601a7 |
| Source note | uspto-grants-2006_03 |