HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-amino-2-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]benzonitrile → HCID 22228073, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-amino-2-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]benzonitrile | HCID 21942323 | — |
| Reactant | 1-(4-Fluorophenyl)pyrrole-3-carboxylic acid | HCID 22228040 | — |
| Product | HCID 22228073 | HCID 22228073 | 57.8% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 64 using 1-(4-fluorophenyl)pyrrole-3-carboxylic acid (0.3 g) and 5-amino-2-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]benzonitrile (0.5 g), the title compound (0.4 g) was obtained, melting point: 240° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07015218B1 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-ba5cfece0e674e729737a9c882f9ddc5 |
| Source note | uspto-grants-2006_03 |