HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-Methyl-1-phenylpyrazole-4-carboxylic acid → N-{3-Cyano-4-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]phenyl}-5-methyl-1-phenylpyrazole-4-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 5-Methyl-1-phenylpyrazole-4-carboxylic acid | HCID 145221 | — |
| Edukt | 5-amino-2-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]benzonitrile | HCID 21942323 | — |
| Produkt | N-{3-Cyano-4-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]phenyl}-5-methyl-1-phenylpyrazole-4-carboxamide | HCID 21018364 | 69,6% |
Reaktionsschritte
By the reaction and treatment in the same manner as in Example 64 using 5-methyl-1-phenylpyrazole-4-carboxylic acid (0.5 g) and 5-amino-2-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]benzonitrile (0.7 g), the title compound (0.8 g) was obtained, melting point: 227° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07015218B1 |
| Quelldatensatz | uspto-grants-2006_03 |
| ORD ID | ord-c1c7c56da8bc4531a2a2546e0921b2a5 |
| Quellennotiz | uspto-grants-2006_03 |