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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1744666Erstellt: 25. Oktober 2026

5-Methyl-1-phenylpyrazole-4-carboxylic acid → N-{3-Cyano-4-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]phenyl}-5-methyl-1-phenylpyrazole-4-carboxamide

https://huagongshe.com/reaction/1744666

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt5-Methyl-1-phenylpyrazole-4-carboxylic acidHCID 145221—
Edukt5-amino-2-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]benzonitrileHCID 21942323—
ProduktN-{3-Cyano-4-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]phenyl}-5-methyl-1-phenylpyrazole-4-carboxamideHCID 2101836469,6%

Reaktionsschritte

By the reaction and treatment in the same manner as in Example 64 using 5-methyl-1-phenylpyrazole-4-carboxylic acid (0.5 g) and 5-amino-2-[4-(3,4,5,6-tetrahydro-2H-pyran-4-yl)piperazin-1-yl]benzonitrile (0.7 g), the title compound (0.8 g) was obtained, melting point: 227° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07015218B1
Quelldatensatzuspto-grants-2006_03
ORD IDord-c1c7c56da8bc4531a2a2546e0921b2a5
Quellennotizuspto-grants-2006_03