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HRID 1744672作成日：2026年10月25日

1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride → 1-(4-Chlorophenyl)-N-[3-cyano-4-(3-morpholinopropoxy)phenyl]-5-methylpyrazole-4-carboxamide

https://huagongshe.com/reaction/1744672

反応式

関与物質

役割名称HCID仕込み量
反応物1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chlorideHCID 2776128—
反応物5-Amino-2-(3-morpholinopropoxy)benzonitrileHCID 22228085—
生成物1-(4-Chlorophenyl)-N-[3-cyano-4-(3-morpholinopropoxy)phenyl]-5-methylpyrazole-4-carboxamideHCID 2222821625.1%

反応手順

By the reaction and treatment in the same manner as in Example 150 using 1-(4-chlorophenyl)-5-methylpyrazole-4-carboxylic chloride (0.74 g) and 5-amino-2-(3-morpholinopropoxy) benzonitrile (0.76 g), the title compound (0.35 g) was obtained, melting point: 155–157° C.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07015218B1
出典データセットuspto-grants-2006_03
ORD IDord-b75d2469bd424e68a73b17e6aab2d9a5
出典メモuspto-grants-2006_03