Benzylamine → HCID 10414655, compound

Participants

Reaction Steps

To a solution of benzylamine (0.0536 g; 0.50mmol) and a drop of triethylamine in 5 mL of methylene chloride, compound L (0.043 g; 0.094 mmol) in 3 mL of methylene chloride was added at room temperature. The reaction mixture was stirred for 2 h and then diluted with 10 mL of methylene chloride and 10 mL of water. The organic phase was dried over CaCl2, concentrated and the crude reaction mixture purified by silica gel column chromatography (eluant: CH2Cl2/CH3OH=190/10) to yield compound 15 (0.039 g; 78%).

Provenance & Evidence