反应详情

To a solution of the above alcohol (1 eq) in CH2Cl2 (0.3M) at rt was added Dess-Martin periodinane (1.5 eq). The reaction mixture was stirred for 45 minutes at rt and H2O (10 eq) was added. The mixture was stirred for 30 minutes and filtered through silica gel pad eluted with 30% EtOAc/hexane and concentrated. The residue was purified by flash chromatography on silica gel eluted with 20% EtOAc/hexane to give the title compound.

1. stirringThe mixture was stirred for 30 minutes
2. filtrationfiltered through silica gel pad
3. washeluted with 30% EtOAc/hexane
4. concentrationconcentrated
5. customThe residue was purified by flash chromatography on silica gel
6. washeluted with 20% EtOAc/hexane