HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-9-ethylcarbazole → (2S,4EZ)-4-(ethoxyimino)-N-(9-ethyl-9H-carbazol-3-yl)-1-(-phenoxyacetyl)-2-pyrrolidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-9-ethylcarbazole | HCID 8588 | — |
| Reactant | Phenoxyacetic Acid | HCID 19188 | — |
| Reactant | (2S,4EZ)-1-(tertbutoxycarbonyl)-4-(ethoxyirnino)-2-pyrrolidinecarboxylic acid | HCID 58714540 | — |
| Product | (2S,4EZ)-4-(ethoxyimino)-N-(9-ethyl-9H-carbazol-3-yl)-1-(-phenoxyacetyl)-2-pyrrolidinecarboxamide | HCID 131725399 | — |
Reaction Steps
Following the general method as outlined in Example 2, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(ethoxyimino)-2-pyrrolidinecarboxylic acid, phenoxyacetic acid, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained after column chromatography as an off-white solid as a mixture of E/Z-isomers. The isomers were then separated using column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018988B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-6fb986f8c4c242d2ae2ad86ae9e14760 |
| Source note | uspto-grants-2006_03 |