HRID1745035

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID60993

2-Aminoethyldiethylamine

C6H16N2

HCID74193

Benzoyl chloride, 4-phenoxy-

C13H9ClO2

结构：CC(C)(C)OC(=O)N1CC(=NOCc2ccccc2)C[C@H]1C(=O)O

HCID131725420

未命名化合物

PRODUCTS

生成物

结构：CCN(CC)CCNC(=O)[C@@H]1CC(=NOCc2ccccc2)CN1C(=O)c1ccc(Oc2ccccc2)cc1

HCID131725421

未命名化合物

PROCEDURE

实验过程

Following the general method as outlined in Example 22, starting from (2S,4EZ)-4-[(benzyloxy)imino]-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid, 4-phenoxybenzoyl chloride, and N1,N1-diethyl-1,2-ethanediamine the title compound was obtained in 86% purity by LC/MS. MS(ESI+): m/z=529.6.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-88baf07a4c8a42dea8eb19a1beb7f0e2
来源数据集: uspto-grants-2006_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07018988B2
来源说明: uspto-grants-2006_03

反应 SMILES

[CH2:1]([O:8][N:9]=[C:10]1[CH2:14][N:13]([C:15]([O:17]C(C)(C)C)=O)[C@H:12]([C:22]([OH:24])=O)[CH2:11]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[O:25]([C:32]1[CH:40]=[CH:39][C:35](C(Cl)=O)=[CH:34][CH:33]=1)[C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1.[CH2:41]([N:43]([CH2:47][CH3:48])[CH2:44][CH2:45][NH2:46])[CH3:42]>>[CH2:1]([O:8][N:9]=[C:10]1[CH2:14][N:13]([C:15](=[O:17])[C:35]2[CH:34]=[CH:33][C:32]([O:25][C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)=[CH:40][CH:39]=2)[C@H:12]([C:22]([NH:46][CH2:45][CH2:44][N:43]([CH2:47][CH3:48])[CH2:41][CH3:42])=[O:24])[CH2:11]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1