HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allylamine → (2S,4EZ)-N-allyl-4-{[(3,4-dichlorobenzyl)oxy]imino}-(diphenylacetyl)-2-pyrrolidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allylamine | HCID 7853 | — |
| Reactant | 2,2-Diphenylacetyl chloride | HCID 74637 | — |
| Reactant | (2S,4EZ)-1-(tert-butoxycarbonyl)-4-{[(3,4-dichlorobenzyl)oxy]imino}-2-pyrrolidinecarboxylic acid | HCID 131725417 | — |
| Product | (2S,4EZ)-N-allyl-4-{[(3,4-dichlorobenzyl)oxy]imino}-(diphenylacetyl)-2-pyrrolidinecarboxamide | HCID 131725453 | — |
Reaction Steps
Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-{[(3,4-dichlorobenzyl)oxy]imino}-2-pyrrolidinecarboxylic acid, diphenylacetyl chloride, and allylamine the title compound was obtained in 54% purity by LC)MS. MS(ESI+): m/z=536.6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018988B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-78dffaff8b424814adb5a45a4fde285e |
| Source note | uspto-grants-2006_03 |