HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Naphthalenemethanamine → (2S,4EZ)-4-[(benzyloxy)imino]-N-(1-naphthylmethyl)-1-(phenoxyacetyl)-2-pyrrolidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Naphthalenemethanamine | HCID 8355 | — |
| Reactant | Phenoxyacetyl chloride | HCID 69703 | — |
| Reactant | (2S,4EZ)-4[(benzyloxy)imino]-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid | HCID 131725420 | — |
| Product | (2S,4EZ)-4-[(benzyloxy)imino]-N-(1-naphthylmethyl)-1-(phenoxyacetyl)-2-pyrrolidinecarboxamide | HCID 131725469 | — |
Reaction Steps
Following the general method as outlined in Example 22, starting from (2S,4EZ)-4-[(benzyloxy)imino]-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid, phenoxyacetyl chloride, and 1-naphthylmethylamine the title compound was obtained in 74% purity by LC/MS. MS(ESI+): m/z=508.4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018988B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-c3b85f32c6674806b0a959f854e9f4e7 |
| Source note | uspto-grants-2006_03 |