HRID1745106

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8588

3-Amino-9-ethylcarbazole

C14H14N2

HCID78210

Benzoyl isocyanate

C8H5NO2

结构：CC(C)(C)OC(=O)N1CC(=CC#N)C[C@H]1C(=O)O

HCID69250314

未命名化合物

PRODUCTS

生成物

结构：CCn1c2ccccc2c2cc(NC(=O)[C@@H]3CC(=CC#N)CN3C(=O)NC(=O)c3ccccc3)ccc21

HCID69250222

未命名化合物

PROCEDURE

实验过程

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(cyanomethylene)-2-pyrrolidinecarboxylic acid, benzoyl isocyanate, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 74% purity by LC/MS. MS(ESI+): m/z=492.4.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f7489f161b024e03be94d33478034f10
来源数据集: uspto-grants-2006_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07018988B2
来源说明: uspto-grants-2006_03

反应 SMILES

C(O[C:6]([N:8]1[CH2:12][C:11](=[CH:13][C:14]#[N:15])[CH2:10][C@H:9]1[C:16]([OH:18])=O)=[O:7])(C)(C)C.[C:19]([N:27]=C=O)(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[CH2:30]([N:32]1[C:44]2[CH:43]=[CH:42][C:41]([NH2:45])=[CH:40][C:39]=2[C:38]2[C:33]1=[CH:34][CH:35]=[CH:36][CH:37]=2)[CH3:31]>>[C:19]([NH:27][C:6]([N:8]1[CH2:12][C:11](=[CH:13][C:14]#[N:15])[CH2:10][C@H:9]1[C:16]([NH:45][C:41]1[CH:42]=[CH:43][C:44]2[N:32]([CH2:30][CH3:31])[C:33]3[C:38]([C:39]=2[CH:40]=1)=[CH:37][CH:36]=[CH:35][CH:34]=3)=[O:18])=[O:7])(=[O:26])[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1