3-Amino-9-ethylcarbazole → HCID 69248883, compound

HRID 1745112Notes

Reaction equation

HRID 1745112 reaction equation
C(O[C:6]([N:8]1[CH2:15][C:14](=[CH2:16])[CH2:13][C@H:9]1[C:10]([OH:12])=O)=[O:7])(C)(C)C.[N:17]([C:20]1[CH:25]=[CH:24][CH:23]=[C:22]([O:26][CH3:27])[CH:21]=1)=C=O.[CH2:28]([N:30]1[C:42]2[CH:41]=[CH:40][C:39]([NH2:43])=[CH:38][C:37]=2[C:36]2[C:31]1=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH3:29]>>[CH2:28]([N:30]1[C:42]2[CH:41]=[CH:40][C:39]([NH:43][C:10]([C@@H:9]3[CH2:13][C:14](=[CH2:16])[CH2:15][N:8]3[C:6]([NH:17][C:20]3[CH:25]=[CH:24][CH:23]=[C:22]([O:26][CH3:27])[CH:21]=3)=[O:7])=[O:12])=[CH:38][C:37]=2[C:36]2[C:31]1=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH3:29]

Participants

4

Reactant 3

HCID 85883-Amino-9-ethylcarbazoleHCID 878433-Methoxyphenyl isocyanateHCID 21727417(2S)-1-((tert-butoxy)carbonyl)-4-methylidenepyrrolidine-2-carboxylic acid

Product 1

HCID 69248883HCID 69248883, compound

Procedure

Following the general method as outlined in Example 22, starting from 1-(tert-butoxycarbonyl)-4-methyleneproline, 1-isocyanato-3-methoxybenzene, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 47% purity by LC/MS. MS(ESI+): m/z=469.4.

Sources & evidence

ORD record
ord-1aed28a75d2044a58e18efc3c5762ab7
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

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