N,N-Diethylethylenediamine → HCID 131725478, compound

HRID 1745114Notes

Reaction equation

HRID 1745114 reaction equation
C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH3:15])[CH2:10][C@H:9]1[C:16]([OH:18])=O)=[O:7])(C)(C)C.[C:19]([C:21]1[CH:29]=[CH:28][C:24](C(Cl)=O)=[CH:23][CH:22]=1)#[N:20].[CH2:30]([N:32]([CH2:36][CH3:37])[CH2:33][CH2:34][NH2:35])[CH3:31]>>[C:19]([C:21]1[CH:22]=[CH:23][C:24]([C:6]([N:8]2[CH2:12][C:11](=[N:13][O:14][CH3:15])[CH2:10][C@H:9]2[C:16]([NH:35][CH2:34][CH2:33][N:32]([CH2:36][CH3:37])[CH2:30][CH3:31])=[O:18])=[O:7])=[CH:28][CH:29]=1)#[N:20]

Participants

4

Reactant 3

HCID 60993N,N-DiethylethylenediamineHCID 801724-Cyanobenzoyl chlorideHCID 58714586(2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid

Product 1

HCID 131725478HCID 131725478, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, 4-cyanobenzoyl chloride, and N1,N1-diethyl-1,2-ethanediamine the title compound was obtained in 58% purity by LC/MS. MS(ESI+): m/z=386.2.

Sources & evidence

ORD record
ord-a958c0549dcc4dee9ec6c4a4a371100b
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

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