3-Amino-9-ethylcarbazole → HCID 69250761, compound

HRID 1745122Notes

Reaction equation

HRID 1745122 reaction equation
C(O[C:6]([N:8]1[CH2:15][C:14](=[CH2:16])[CH2:13][C@H:9]1[C:10]([OH:12])=O)=[O:7])(C)(C)C.[Cl:17][C:18]1[CH:23]=[C:22]([N:24]=C=O)[CH:21]=[C:20]([Cl:27])[CH:19]=1.[CH2:28]([N:30]1[C:42]2[CH:41]=[CH:40][C:39]([NH2:43])=[CH:38][C:37]=2[C:36]2[C:31]1=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH3:29]>>[Cl:17][C:18]1[CH:23]=[C:22]([NH:24][C:6]([N:8]2[CH2:15][C:14](=[CH2:16])[CH2:13][C@H:9]2[C:10]([NH:43][C:39]2[CH:40]=[CH:41][C:42]3[N:30]([CH2:28][CH3:29])[C:31]4[C:36]([C:37]=3[CH:38]=2)=[CH:35][CH:34]=[CH:33][CH:32]=4)=[O:12])=[O:7])[CH:21]=[C:20]([Cl:27])[CH:19]=1

Participants

4

Reactant 3

HCID 85883-Amino-9-ethylcarbazoleHCID 944603,5-Dichlorophenyl isocyanateHCID 21727417(2S)-1-((tert-butoxy)carbonyl)-4-methylidenepyrrolidine-2-carboxylic acid

Product 1

HCID 69250761HCID 69250761, compound

Procedure

Following the general method as outlined in Example 22, starting from 1-(tert-butoxycarbonyl)-4-methyleneproline, 1,3-dichloro-5-isocyanatobenzene, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 40% purity by LC/MS. MS(ESI+): m/z=507.6.

Sources & evidence

ORD record
ord-8f789dd8173f487d8b0917daea03c7f3
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

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