Benzoyl chloride → HCID 69249896, compound

HRID 1745124Notes

Reaction equation

HRID 1745124 reaction equation
C(O[C:6]([N:8]1[CH2:12][C:11](=[CH:13][Cl:14])[CH2:10][C@H:9]1[C:15]([OH:17])=O)=[O:7])(C)(C)C.C(Cl)(=O)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[CH2:27]([N:29]1[C:41]2[CH:40]=[CH:39][C:38]([NH2:42])=[CH:37][C:36]=2[C:35]2[C:30]1=[CH:31][CH:32]=[CH:33][CH:34]=2)[CH3:28]>>[C:6]([N:8]1[CH2:12][C:11](=[CH:13][Cl:14])[CH2:10][C@H:9]1[C:15]([NH:42][C:38]1[CH:39]=[CH:40][C:41]2[N:29]([CH2:27][CH3:28])[C:30]3[C:35]([C:36]=2[CH:37]=1)=[CH:34][CH:33]=[CH:32][CH:31]=3)=[O:17])(=[O:7])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

4

Reactant 3

HCID 7412Benzoyl chlorideHCID 85883-Amino-9-ethylcarbazoleHCID 69251379HCID 69251379, compound

Product 1

HCID 69249896HCID 69249896, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(chloromethylene)-2-pyrrolidinecarboxylic acid, benzoyl chloride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 48% purity by LC/MS. MS(ESI+): m/z=458.4.

Sources & evidence

ORD record
ord-07e73b12f6a14f45a7fb6e8e05b8deee
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

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