3-Amino-9-ethylcarbazole → HCID 69247759, compound

HRID 1745127Notes

Reaction equation

HRID 1745127 reaction equation
C(O[C:6]([N:8]1[CH2:15][C:14](=[CH2:16])[CH2:13][C@H:9]1[C:10]([OH:12])=O)=[O:7])(C)(C)C.[Cl:17][C:18]1[CH:28]=[CH:27][C:21]([O:22][CH2:23]C(Cl)=O)=[CH:20][CH:19]=1.[CH2:29]([N:31]1[C:43]2[CH:42]=[CH:41][C:40]([NH2:44])=[CH:39][C:38]=2[C:37]2[C:32]1=[CH:33][CH:34]=[CH:35][CH:36]=2)[CH3:30]>>[Cl:17][C:18]1[CH:28]=[CH:27][C:21]([O:22][CH2:23][C:6]([N:8]2[CH2:15][C:14](=[CH2:16])[CH2:13][C@H:9]2[C:10]([NH:44][C:40]2[CH:41]=[CH:42][C:43]3[N:31]([CH2:29][CH3:30])[C:32]4[C:37]([C:38]=3[CH:39]=2)=[CH:36][CH:35]=[CH:34][CH:33]=4)=[O:12])=[O:7])=[CH:20][CH:19]=1

Participants

4

Reactant 3

HCID 85883-Amino-9-ethylcarbazoleHCID 77771p-Chlorophenoxyacetyl chlorideHCID 21727417(2S)-1-((tert-butoxy)carbonyl)-4-methylidenepyrrolidine-2-carboxylic acid

Product 1

HCID 69247759HCID 69247759, compound

Procedure

Following the general method as outlined in Example 22, starting from 1-(tert-butoxycarbonyl)-4-methyleneproline, (4-chlorophenoxy)acetyl chloride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 100% purity by LC/MS. MS(ESI+): m/z=488.4.

Sources & evidence

ORD record
ord-6909ef22068d45eca65f3f5c3054180e
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

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