3-Amino-9-ethylcarbazole → HCID 131725495, compound

HRID 1745147Notes

Reaction equation

HRID 1745147 reaction equation
[CH2:1]([O:8][N:9]=[C:10]1[CH2:14][N:13]([C:15]([O:17]C(C)(C)C)=O)[C@H:12]([C:22]([OH:24])=O)[CH2:11]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N:25]([CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])=C=O.[CH2:33]([N:35]1[C:47]2[CH:46]=[CH:45][C:44]([NH2:48])=[CH:43][C:42]=2[C:41]2[C:36]1=[CH:37][CH:38]=[CH:39][CH:40]=2)[CH3:34]>>[CH2:1]([O:8][N:9]=[C:10]1[CH2:14][N:13]([C:15]([NH:25][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])=[O:17])[C@H:12]([C:22]([NH:48][C:44]2[CH:45]=[CH:46][C:47]3[N:35]([CH2:33][CH3:34])[C:36]4[C:41]([C:42]=3[CH:43]=2)=[CH:40][CH:39]=[CH:38][CH:37]=4)=[O:24])[CH2:11]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 85883-Amino-9-ethylcarbazoleHCID 206036Pentane, 1-isocyanato-HCID 131725420(2S,4EZ)-4[(benzyloxy)imino]-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid

Product 1

HCID 131725495HCID 131725495, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-4-[(benzyloxy)imino]-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid, 1-isocyanatopentane, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 63% purity by LC/MS. MS(ESI+): m/z=540.4.

Sources & evidence

ORD record
ord-915bbda3f88a4cad81178a9da5c6a15e
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

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