3-Amino-9-ethylcarbazole → HCID 131725504, compound

HRID 1745156Notes

Reaction equation

HRID 1745156 reaction equation
C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH2:15][CH3:16])[CH2:10][C@H:9]1[C:17]([OH:19])=O)=[O:7])(C)(C)C.[N:20]([C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([O:29][CH3:30])[CH:24]=1)=C=O.[CH2:31]([N:33]1[C:45]2[CH:44]=[CH:43][C:42]([NH2:46])=[CH:41][C:40]=2[C:39]2[C:34]1=[CH:35][CH:36]=[CH:37][CH:38]=2)[CH3:32]>>[CH2:15]([O:14][N:13]=[C:11]1[CH2:12][N:8]([C:6]([NH:20][C:23]2[CH:28]=[CH:27][CH:26]=[C:25]([O:29][CH3:30])[CH:24]=2)=[O:7])[C@H:9]([C:17]([NH:46][C:42]2[CH:43]=[CH:44][C:45]3[N:33]([CH2:31][CH3:32])[C:34]4[C:39]([C:40]=3[CH:41]=2)=[CH:38][CH:37]=[CH:36][CH:35]=4)=[O:19])[CH2:10]1)[CH3:16]

Participants

4

Reactant 3

HCID 85883-Amino-9-ethylcarbazoleHCID 878433-Methoxyphenyl isocyanateHCID 58714540(2S,4EZ)-1-(tertbutoxycarbonyl)-4-(ethoxyirnino)-2-pyrrolidinecarboxylic acid

Product 1

HCID 131725504HCID 131725504, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(ethoxyimino)-2-pyrrolidinecarboxylic acid, 1-isocyanato-3-methoxybenzene, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 60% purity by LC/MS. MS(ESI+): m/z=514.4.

Sources & evidence

ORD record
ord-f4d8949b605642e8a8f9e7af9df4f81b
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

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