3-Amino-9-ethylcarbazole → HCID 131725505, compound

HRID 1745157Notes

Reaction equation

HRID 1745157 reaction equation
C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH2:15][CH3:16])[CH2:10][C@H:9]1[C:17]([OH:19])=O)=[O:7])(C)(C)C.[Cl:20][C:21]1[CH:31]=[CH:30][C:24]([O:25][CH2:26]C(Cl)=O)=[CH:23][CH:22]=1.[CH2:32]([N:34]1[C:46]2[CH:45]=[CH:44][C:43]([NH2:47])=[CH:42][C:41]=2[C:40]2[C:35]1=[CH:36][CH:37]=[CH:38][CH:39]=2)[CH3:33]>>[Cl:20][C:21]1[CH:31]=[CH:30][C:24]([O:25][CH2:26][C:6]([N:8]2[CH2:12][C:11](=[N:13][O:14][CH2:15][CH3:16])[CH2:10][C@H:9]2[C:17]([NH:47][C:43]2[CH:44]=[CH:45][C:46]3[N:34]([CH2:32][CH3:33])[C:35]4[C:40]([C:41]=3[CH:42]=2)=[CH:39][CH:38]=[CH:37][CH:36]=4)=[O:19])=[O:7])=[CH:23][CH:22]=1

Participants

4

Reactant 3

HCID 85883-Amino-9-ethylcarbazoleHCID 77771p-Chlorophenoxyacetyl chlorideHCID 58714540(2S,4EZ)-1-(tertbutoxycarbonyl)-4-(ethoxyirnino)-2-pyrrolidinecarboxylic acid

Product 1

HCID 131725505HCID 131725505, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(ethoxyimino)-2-pyrrolidinecarboxylic acid, (4-chlorophenoxy)acetyl chloride, and 9-ethyl-9H-carbazol-3-amine the title compound was obtained in 100% purity by LC/MS. MS(ESI+): m/z=533.4.

Sources & evidence

ORD record
ord-66ef843239584aa5ae780dbcd284dd0d
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

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