N,N-Diethylethylenediamine → HCID 131725566, compound

HRID 1745234Notes

Reaction equation

HRID 1745234 reaction equation
C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][CH:17]=2)[CH2:10][C@H:9]1[C:24]([OH:26])=O)=[O:7])(C)(C)C.[CH3:27][N:28]([CH3:35])[CH2:29][CH2:30][CH2:31]C(Cl)=O.[CH2:36]([N:38]([CH2:42][CH3:43])[CH2:39][CH2:40][NH2:41])[CH3:37]>>[CH2:36]([N:38]([CH2:42][CH3:43])[CH2:39][CH2:40][NH:41][C:24]([C@@H:9]1[CH2:10][C:11](=[N:13][O:14][CH2:15][C:16]2[CH:17]=[CH:18][C:19]([O:22][CH3:23])=[CH:20][CH:21]=2)[CH2:12][N:8]1[C:6](=[O:7])[CH2:31][CH2:30][CH2:29][N:28]([CH3:35])[CH3:27])=[O:26])[CH3:37]

Participants

4

Reactant 3

HCID 60993N,N-DiethylethylenediamineHCID 150876904-(Dimethylamino)butanoyl chlorideHCID 58714542HCID 58714542, compound

Product 1

HCID 131725566HCID 131725566, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-{[(4-methoxybenzyl)oxy]imino}-2-pyrrolidinecarboxylic acid, 4-(dimethylamino)butanoyl chloride, and N1,N1-diethyl-1,2-ethanediamine the title compound was obtained in 100% purity by LC/MS. MS(ESI+): m/z=476.2.

Sources & evidence

ORD record
ord-92096c06813748fdb40c848b90bf6dad
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

Loading…