Ethanolamine → HCID 131725673, compound

HRID 1745347Notes

Reaction equation

HRID 1745347 reaction equation
C(O[C:6]([N:8]1[CH2:12][C:11](=[N:13][O:14][CH3:15])[CH2:10][C@H:9]1[C:16]([OH:18])=O)=[O:7])(C)(C)C.C(O)(=O)[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27].[NH2:30][CH2:31][CH2:32][OH:33]>>[OH:33][CH2:32][CH2:31][NH:30][C:16]([C@@H:9]1[CH2:10][C:11](=[N:13][O:14][CH3:15])[CH2:12][N:8]1[C:6](=[O:7])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH3:20])=[O:18]

Participants

4

Reactant 3

HCID 700EthanolamineHCID 8158Nonanoic AcidHCID 58714586(2S,4EZ)-1(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid

Product 1

HCID 131725673HCID 131725673, compound

Procedure

Following the general method as outlined in Example 22, starting from (2S,4EZ)-1-(tert-butoxycarbonyl)-4-(methoxyimino)-2-pyrrolidinecarboxylic acid, nonanoic acid, and 2-aminoethanol, the title compound was obtained in 93% purity by HPLC. MS(ESI+): m/z=342.

Sources & evidence

ORD record
ord-8208de65d3c641f5b139900162576c76
Source dataset
uspto-grants-2006_03
Patent number
US07018988B2

Reaction notes

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