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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1745442Generated: October 31, 2026

4-(Trifluoromethoxy)phenylboronic acid → (3-Nitro-4'-trifluoromethoxy-biphenyl-4-yl)-carbamic acid tert.-butyl ester

https://huagongshe.com/reaction/1745442

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethoxy)phenylboronic acidHCID 2734386—
ReactantTert-butyl (4-iodo-2-nitrophenyl)carbamateHCID 23554339—
Product(3-Nitro-4'-trifluoromethoxy-biphenyl-4-yl)-carbamic acid tert.-butyl esterHCID 69592811—

Reaction Steps

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) and 4-(trifluoromethoxy)benzene boronic acid according to the general procedure B. Obtained as an orange solid (569 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07018998B2
Source datasetuspto-grants-2006_03
ORD IDord-8333a7109dc6478cab8c08feb30bd08d
Source noteuspto-grants-2006_03