HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,3-Difluorophenyl)boronic acid → (2',3'-Difluoro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,3-Difluorophenyl)boronic acid | HCID 2734333 | — |
| Reactant | Tert-butyl (4-iodo-2-nitrophenyl)carbamate | HCID 23554339 | — |
| Product | (2',3'-Difluoro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester | HCID 69592780 | 91.9% |
Reaction Steps
Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) (3.64 g, 10 mmol) and 2,3-difluorobenzene boronic acid (2.35 g, 14.9 mmol) according to the general procedure B. Obtained as a yellow solid (3.22 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018998B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-f51540c25ae340ca85512336e6ac473f |
| Source note | uspto-grants-2006_03 |