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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1745455Generated: October 31, 2026

2-Iodothiophene → tert-Butyl 2-nitro-4-(thiophen-2-yl)phenylcarbamate

https://huagongshe.com/reaction/1745455

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-IodothiopheneHCID 18921—
ReactantBis(pinacolato)diboraneHCID 2733548—
ReactantTert-butyl (4-iodo-2-nitrophenyl)carbamateHCID 23554339—
Producttert-Butyl 2-nitro-4-(thiophen-2-yl)phenylcarbamateHCID 59736984—

Reaction Steps

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1), bis(pinacolato)diboron and 2-iodothiophene according to the general procedure C. Obtained as a yellow solid (91 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07018998B2
Source datasetuspto-grants-2006_03
ORD IDord-1c0562c7060344fd94f4af1bca15c63f
Source noteuspto-grants-2006_03