HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Difluoro-1-iodobenzene → [4-(2,4-Difluoro-phenylethynyl)-2-nitro-phenyl]-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Difluoro-1-iodobenzene | HCID 137519 | — |
| Reactant | tert-Butyl (4-ethynyl-2-nitrophenyl)carbamate | HCID 23554338 | — |
| Product | [4-(2,4-Difluoro-phenylethynyl)-2-nitro-phenyl]-carbamic acid tert.-butyl ester | HCID 69592795 | 107.8% |
Reaction Steps
Prepared from (4-ethynyl-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example F2) (525 mg, 2.0 mmol) and 2,4-difluoro-1-iodobenzene (0.36 mL, 3 mmol) according to the general procedure F. Obtained as a yellow solid (807 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018998B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-f7e1cf7dbfee456d8d60c6a7ccec4b7a |
| Source note | uspto-grants-2006_03 |