Carbamic acid, (2′-methoxy-3-nitro[1,1′-biphenyl]-4-yl)-, 1,1-dimethylethyl ester → HCID 69592878, compound

HRID 1745490Notes

Reaction equation

HRID 1745490 reaction equation
[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[O:20][CH3:21])=[CH:10][C:9]=1[N+:22]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:25])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[O:20][CH3:21])=[CH:10][C:9]=1[NH2:22])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 69592784Carbamic acid, (2′-methoxy-3-nitro[1,1′-biphenyl]-4-yl)-, 1,1-dimethylethyl ester

Product 1

HCID 69592878HCID 69592878, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

Prepared from (2′-methoxy-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example C1) by catalytic hydrogenation with Raney-Ni according to the general procedure G (method a). Obtained as a white solid (169 mg).

Sources & evidence

ORD record
ord-6b1bb878862d46a786089c59ee90786d
Source dataset
uspto-grants-2006_03
Patent number
US07018998B2

Reaction notes

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