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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1745638Generated: November 3, 2026

HCID 22224751, compound → {2-[3-(2-Cyano-pyridin-4-yl)-3-oxo-propionylamino]-4-cyclopropyl-phenyl}-carbamic acid tert.-butyl ester

https://huagongshe.com/reaction/1745638

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22224751HCID 22224751—
Reactant(2-Amino-4-cyclopropyl-phenyl)-carbamic acid tert-butyl esterHCID 69592759—
Product{2-[3-(2-Cyano-pyridin-4-yl)-3-oxo-propionylamino]-4-cyclopropyl-phenyl}-carbamic acid tert.-butyl esterHCID 86588064—

Reaction Steps

Prepared from (2-amino-4-cyclopropyl-phenyl)-carbamic acid tert.-butyl ester (Example G48) and 4-(2,2-dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-pyridine-2-carbonitrile (Example J16) according to the general procedure K. Obtained as a light brown solid (148 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07018998B2
Source datasetuspto-grants-2006_03
ORD IDord-6e040ee265e942d1b3f181d1a89016af
Source noteuspto-grants-2006_03