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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1745643Generated: October 30, 2026

Tert-butyl (3-amino-4'-fluoro-[1,1'-biphenyl]-4-YL)carbamate → HCID 86588069, compound

https://huagongshe.com/reaction/1745643

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl (3-amino-4'-fluoro-[1,1'-biphenyl]-4-YL)carbamateHCID 59737201—
Reactant3-[3-(3-Methyl-isoxazol-5-yl)-phenyl)-3-oxo-propionic acid tert-butyl esterHCID 69592871—
ProductHCID 86588069HCID 8658806932.5%

Reaction Steps

Prepared from (3-amino-4′-fluoro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example G39) (151 mg, 0.5 mmol) and 3-[3-(3-methyl-isoxazol-5-yl)-phenyl]-3-oxo-propionic acid tert.-butyl ester (Example H14) (190 mg, 0.63 mmol) according to the general procedure K. Obtained as an off-white solid (86 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07018998B2
Source datasetuspto-grants-2006_03
ORD IDord-2e612a4495d3438b9b9a9ca9b5c9a494
Source noteuspto-grants-2006_03