HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl (3-amino-2'-fluoro-[1,1'-biphenyl]-4-yl)carbamate → HCID 86588078, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl (3-amino-2'-fluoro-[1,1'-biphenyl]-4-yl)carbamate | HCID 67361423 | — |
| Reactant | 3-[3-(3-Methyl-isoxazol-5-yl)-phenyl)-3-oxo-propionic acid tert-butyl ester | HCID 69592871 | — |
| Product | HCID 86588078 | HCID 86588078 | 80.4% |
Reaction Steps
Prepared from (3-amino-2′-fluoro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example G37) (151 mg, 0.5 mmol) and 3-[3-(3-methyl-isoxazol-5-yl)-phenyl]-3-oxo-propionic acid tert.-butyl ester (Example H14) (190 mg, 0.63 mmol) according to the general procedure K. Obtained as a white solid (213 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018998B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-3384fede79c748639133982c105b73c0 |
| Source note | uspto-grants-2006_03 |