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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1745767Generated: November 1, 2026

Trifluoroacetic acid → HCID 22224938, compound

https://huagongshe.com/reaction/1745767

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86588077HCID 86588077—
SolventDichloromethaneHCID 6344—
ProductHCID 22224938HCID 22224938—

Reaction Steps

Prepared from {3-[3-(3-cyano-phenyl)-3-oxo-propionylamino]-2′,5′-difluoro-biphenyl-4-yl}-carbamic acid tert.-butyl ester (Example K92) by treatment with TFA in CH2Cl2 according to the general procedure M. Obtained as a light yellow solid (49 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07018998B2
Source datasetuspto-grants-2006_03
ORD IDord-ccd9d54677854c85801b60617e4be4b7
Source noteuspto-grants-2006_03