HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 22224567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 22224765 | HCID 22224765 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22224567 | HCID 22224567 | 67.6% |
Reaction Steps
Prepared from 3-[7-(3-hydroxy-3-methyl-but-1-ynyl)-4-oxo-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl]-benzonitrile (Example 134) (50 mg, 0.15 mmol) by treatment with TFA in CH2Cl2 according to the general procedure M. Obtained as a sand solid (33 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018998B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-49323cec7af34915b37f797a7e6bdb4b |
| Source note | uspto-grants-2006_03 |