HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 22224781, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | HCID 22224602 | HCID 22224602 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22224781 | HCID 22224781 | 96.3% |
Reaction Steps
Prepared from 3-[4-oxo-7-(1,2,3,6-tetrahydro-pyridin-4-ylethynyl)-4,5-dihydro-3H-benzo[b][1,4]diazepin-2-yl]-benzonitrile (Example 140) (55 mg, 0.15 mmol) by treatment with Ac2O (0.017 mL, 0.165 mmol) in THF (3 mL) at 23° C. for 1 h. Obtained as a sand solid (59 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07018998B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-5e9a4051f80c49bb8df8cf5e0fae6037 |
| Source note | uspto-grants-2006_03 |