HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → 5-Nitro-3-chloro-2,4-difluorobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 3-Chloro-2,4-difluoro-5-nitrobenzoic acid | HCID 15549918 | — |
| Catalyst | Dimethylformamide | HCID 6228 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 5-Nitro-3-chloro-2,4-difluorobenzoyl chloride | HCID 15549919 | — |
Reaction Steps
An amount of 3.47 g (0.015 mole) of 5-nitro-3-chloro-2,4-difluorobenzoic acid and 2.03 g (0.016 mole) of oxalyl chloride are dissolved in 15 ml of dichloromethane then two drops of DMF are added. The reaction is stirred for 14 hours then the solvent is evaporated under vacuum to afford the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07019143B2 |
| Source dataset | uspto-grants-2006_03 |
| ORD ID | ord-670074563d9f48f78e1715903e292551 |
| Source note | uspto-grants-2006_03 |