Ammonia → HCID 22227295, compound

HRID 1745872Notes

Reaction equation

HRID 1745872 reaction equation
[S:1]([C:5]1[CH:25]=[CH:24][CH:23]=[CH:22][C:6]=1[C:7]([O:9][C:10](=O)[C:11]1C=CC=CC=1S(O)(=O)=O)=[O:8])([OH:4])(=[O:3])=[O:2].[NH3:26].CO>C(O)C.CCOCC>[CH2:10]([O:9][C:7]([C:6]1[CH:22]=[CH:23][CH:24]=[CH:25][C:5]=1[S:1]([O-:4])(=[O:2])=[O:3])=[O:8])[CH3:11].[NH4+:26]

Participants

6

Reactant 3

HCID 222AmmoniaHCID 887MethanolHCID 13795534Sulphobenzoic anhydride

Product 1

HCID 22227295HCID 22227295, compoundYield 91%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 3283Diethyl EtherSolvent

Procedure

2-Sulfobenzoic anhydride (1; 50.2 g, 0.270 mol) in 160 ml of absolute ethanol was stirred overnight. After the addition of 60 ml of 7N methanolic ammonia, the mixture was stirred for a further 2 hours and the resulting thick white reaction mixture was clarified by addition of 160 ml of methanol. The solution was diluted with ether (1.1 L) until no more solids precipitated, and the product was collected by filtration and air-dried overnight to give 60.6 g (91% yield) of (2).

Workup

  1. customprecipitated
  2. filtrationthe product was collected by filtration
  3. customair-dried overnight

Sources & evidence

ORD record
ord-bdfdf7b46c17410a9bc84042c2e2f02e
Source dataset
uspto-grants-2006_03
Patent number
US07019175B2

Reaction notes

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