Cyclododecane → Cyclododecanone

Participants

Reaction Steps

To 7.5 ml of acetonitrile were added 504 mg (3.0 mmol) of cyclododecane, 60 mg (0.3 mmol) of N-hydroxysaccharin and 3.9 mg (0.015 mmol) of acetylacetonatocobalt Co(acac)2. The resultant mixture was stirred under an oxygen atmosphere at a temperature of 85° C. for 22 hours. The products in the reaction mixture were analysed by gas chromatography, with cyclododecane being transformed, with a conversion of 28%, into cyclododecanone (selectivity 34.5%, yield 9.5%) and cyclododecanol (selectivity 14%, yield 4%).

Provenance & Evidence