Acetic Acid → Cyclooctanone

Participants

Reaction Steps

To 7.5 ml of acetic acid were added to 336 mg (3.0 mmol) of cyclooctane, 60 mg (0.3 mmol) of N-hydroxysaccharin and 5.3 mg (0.015 mmol) of Fe(acac)3. The resultant mixture was stirred under an oxygen atmosphere at a temperature of 75° C. for 24 hours. The products in the reaction mixture were analysed by gas chromatography, with cyclooctane being transformed, with a conversion of 56%, into cyclooctanone (selectivity 33.5%, yield 19%), cyclooctanol (selectivity 16%, yield 9%), 1,4-cyclooctanedione (selectivity 7%, yield 4%) and octanediacid (selectivity 21%, yield 12%).

Provenance & Evidence