Acetic Acid → Cyclooctanone

Participants

Reaction Steps

To 7.5 ml of acetic acid were added 336 mg (3.0 mmol) of cyclooctane, 60 mg (0.3 mmol) of N-hydroxysaccharin and 5.3 mg (0.015 mmol) of Co(acac)3. The resultant mixture was stirred under an oxygen atmosphere at a temperature of 50° C. for 24 hours. The products in the reaction mixture were analysed by gas chromatography, with cyclooctane being transformed, with a conversion of 53%, into cyclooctanone (selectivity 17.5%, yield 9.5%), cyclooctanol (selectivity 16%, yield 8.5%), 1,4-cyclooctanedione (selectivity 1%, yield 0.5%) and octanediacid (selectivity 20.5%, yield 11%).

Provenance & Evidence