trans-4-Bromo-beta-nitrostyrene → 1-Bromo-4-[(trans)-2-nitrocyclopropyl]benzene

HRID 1746086Notes

Reaction equation

HRID 1746086 reaction equation
C(O[C:9]1[CH:14]=[CH:13][C:12]([C@@H:15]2[CH2:17][C@H:16]2[N+:18]([O-:20])=[O:19])=[CH:11][CH:10]=1)C1C=CC=CC=1.[Br:21]C1C=CC(/C=C/[N+]([O-])=O)=CC=1>>[Br:21][C:9]1[CH:14]=[CH:13][C:12]([C@@H:15]2[CH2:17][C@H:16]2[N+:18]([O-:20])=[O:19])=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 688204trans-4-Bromo-beta-nitrostyreneHCID 666290981-(Benzyloxy)-4-[(trans)-2-nitrocyclopropyl]benzene

Product 1

HCID 670646391-Bromo-4-[(trans)-2-nitrocyclopropyl]benzeneYield 27%

Procedure

This compound was synthesized using the same methodology described in Intermediate C, using the commercially available (E)-1-bromo-4-(2-nitrovinyl)benzene as starting material. Yield: 27%.

Workup

  1. customThis compound was synthesized

Sources & evidence

ORD record
ord-85b300520a914e329fd989200b61832d
Source dataset
uspto-grants-2015_10
Patent number
US09149447B2

Reaction notes

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