HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-Hydroxybenzoate → 3-Phenoxy-4,5-dihydroisoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-Hydroxybenzoate | HCID 88068 | — |
| Reactant | 3-Bromo-4,5-dihydroisoxazole | HCID 21983498 | — |
| Product | 3-Phenoxy-4,5-dihydroisoxazole | HCID 14960467 | — |
Reaction Steps
3-phenoxy-4,5-dihydroisoxazole I-176a and I-176b were prepared in 2 steps from racemic compound I-14. Bromo-4,5-dihydroisoxazole I-14 was reacted with 3-hydroxybenzoic acid methyl ester using Method 5 followed by hydroysis using the analogous conditions as in example 94. [M+H]+=368.0 m/z. Activity: C
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09149465B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-41d7763487704e29b6673e37e80724f6 |
| Source note | uspto-grants-2015_10 |