Trifluoroacetic acid → HCID 86718993, compound

Participants

Reaction Steps

To tert-butyl 2,3-bis(prop-2-ynyloxy)propylcarbamate (I-13a:1.583 g, 5.92 mmol) in CH2Cl2 (23.69 mL) at 0° C. was added TFA (4.56 mL, 59.2 mmol). The mixture was stirred at room temperature for 2 h. Concentrated, and put on pump for 16 h, giving 2,3-bis(prop-2-ynyloxy)propan-1-amine as a yellow oil used as is for next step. LC-MS (M+1) 168.1, t=0.44 minute.

Provenance & Evidence