HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → Methyl 2-nitrobenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | 2-Nitrobenzoic acid | HCID 11087 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | Methyl 2-nitrobenzoate | HCID 69072 | — |
Reaction Steps
A solution of 6-nitro-benzoic acid in benzene was treated with thionyl chloride (2.5 eq) and stirred at reflux for 8 h. After evaporation, the residue was dissolved in chloroform and then treated with methanol. After stirring at reflux for 3 h, the mixture was evaporated to afford compound 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09149477B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-db0c830b03eb471bac94b134e71f3fd1 |
| Source note | uspto-grants-2015_10 |