Tetrabutylammonium Fluoride → HCID 57523002, compound

Participants

Reaction Steps

To a well stirred solution of silyl ether 11 (1.1 g, 2.94 mmol) was added 1 M solution of tetrabutylammonium fluoride (6.2 mL, 5.87 mmol) at 0° C. The reaction mixture was stirred at this temperature for 2 h after which the solvent was removed under reduced pressure and the residue was subjected to column chromatography with petroleum ether/ethyl acetate (5:5 v/v) to afford free alcohol 12 oily liquid.

Provenance & Evidence